oncology APISintaho Pharmaceutical Ltd was established in the year of 2016 and headquartered in Chongqing China, with a grand vison of being the most trusted partner to pharmaceutical companies worldwide. We have a clear focus on developing and manufacturing highly potent and cytotoxic Active Pharmaceutical Ingredients (APIs) and CDMO services.
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<h3>Overview</h3>
<p><strong>Azacitidine</strong> is a synthetic pyrimidine nucleoside analogue used as an antineoplastic agent. Its core manufacturing process involves complex organic synthesis and purification to ensure high purity levels. Molecular formula: C8H13N3O5; CAS No.: 320-67-2.</p>
<h3>Application</h3>
<ul>
<li>Hematologic malignancies treatment, specifically Myelodysplastic Syndromes (MDS).</li>
<li>Acute Myeloid Leukemia (AML) management in eligible patients.</li>
<li>Epigenetic therapy for gene expression modulation in cancer cells.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly contraindicated for use during pregnancy due to teratogenic risks. Requires handling under controlled temperature conditions (2°C–8°C) and protection from light to maintain stability. Medical personnel must utilize appropriate PPE during preparation to prevent dermal exposure.</p>