Artemether 99%(HPLC) CP2010 supplier API Plant extract Pharmaceutical made in china 71963-77-4
AI Product Description
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Artemether is a potent semi-synthetic derivative of artemisinin, isolated from the traditional Chinese medicinal herb *Artemisia annua* (sweet wormwood). With a purity grade of 99% as verified by High-Performance Liquid Chromatography (HPLC), this pharmaceutical-grade API meets the rigorous standards outlined in the Chinese Pharmacopoeia (CP2010). Its molecular formula is C₁₆H₂₆O₅, and it carries the CAS registry number 71967-41-8. This compound is primarily synthesized through the chemical modification of natural artemisinin to enhance its lipophilicity and oral bioavailability compared to its parent compound.
The primary therapeutic application of Artemether lies in the treatment of uncomplicated and severe malaria caused by *Plasmodium falciparum*, including multidrug-resistant strains. It functions by generating free radicals that damage essential proteins and membranes within the malaria parasite, leading to rapid parasite clearance. Due to its fast-acting nature, Artemether is frequently administered in combination with Lumefantrine or other partners as part of Artemisinin-based Combination Therapies (ACTs), which are the global gold standard for malaria management recommended by the World Health Organization. The "made in China" designation highlights its origin from major pharmaceutical manufacturing hubs where advanced extraction and synthesis technologies ensure high-quality production suitable for both domestic and international markets.
Beyond its clinical use in malaria, research continues to explore potential anti-cancer and antiviral properties of artemether derivatives, though these remain investigational. The availability of high-purity Artemether from established Chinese suppliers supports the global supply chain for antimalarial drugs, ensuring consistent efficacy and safety for patients worldwide. Its stability profile and specific pharmacokinetic characteristics make it an indispensable component in modern tropical medicine protocols, effectively reducing mortality rates associated with severe malaria infections in endemic regions.