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CAS NO:
497-76-7
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Basic Info
CAS Number
497-76-7
Pharmacopoeia
In-house Standards
Grade
food grade, pharmaceutical grade
Is Manufacturer
YES
Product Description
Arbutin, also known as ursolic acid, the chemical formula for C12H16O7, is a kind of ericaceae plant extract, bearberry leaves can inhibit the activity of tyrosinase in the body, prevent the formation of melanin, thus reducing the skin pigment deposition, remove spots and freckles, as well as the effect of sterilization, anti-inflammatory, mainly used in cosmetics.
AI Product Description
*The following content is generated by AI and is for reference only.
Arbutin, a naturally occurring glycoside derived primarily from bearberry plants (Arctostaphylos uva-ursi), is widely recognized in the cosmetic and pharmaceutical industries for its potent skin-lightening properties. Its chemical identity is defined by the molecular formula C12H16O7 and the CAS registry number 84380-01-8. Structurally, it consists of hydroquinone linked to a glucose molecule via a beta-glycosidic bond, which serves as a crucial safety mechanism compared to free hydroquinone. This unique structure allows Arbutin to be absorbed safely into the skin while minimizing potential toxicity associated with direct hydroquinone application.
The primary function of Arbutin is the inhibition of tyrosinase, the key enzyme responsible for melanin synthesis within melanocytes. By competitively binding to the active site of this enzyme, Arbutin effectively reduces the production of pigment, leading to a gradual fading of hyperpigmentation, age spots, melasma, and post-inflammatory erythema. Unlike harsher bleaching agents, it operates gently, making it suitable for long-term use in various skincare formulations ranging from serums and creams to lotions. It is particularly favored for addressing uneven skin tone and promoting a more radiant complexion without causing significant irritation or sensitization in most users.
Beyond topical applications, Arbutin has found utility in the food industry as a preservative due to its antimicrobial characteristics, although regulatory limits vary by region. In clinical settings, it is often formulated alongside other antioxidants like Vitamin C and niacinamide to enhance overall efficacy and stability. The white crystalline powder form ensures easy integration into manufacturing processes. As consumer demand shifts toward safer, nature-derived alternatives for brightening, Arbutin remains a gold standard ingredient. Its ability to provide visible results over time, combined with a favorable safety profile, solidifies its status as an essential component in modern dermatological and cosmetic science, offering a reliable solution for those seeking to correct discoloration and achieve a uniform skin texture.
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