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Amtolmetin guacil Nervous system drugs antipyretic analgesic made in china

Category:

Intermediates&Fine Chemicals

CAS NO:

87344-06-7

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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INNER MONGOLIA YUANHONG FINE CHEMICAL CO., LTD.

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Basic Info

CAS Number

87344-06-7

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Samples Provided

Product Description

Amtolmetin guacil Nervous system drugs antipyretic analgesic made in china 87344-06-7

AI Product Description

*The following content is generated by AI and is for reference only.

Amtolmetin guacil is a non-steroidal anti-inflammatory drug (NSAID) belonging to the class of arylpropionic acid derivatives, specifically designed as a prodrug. Chemically known as tolmetin guacil, it is an esterified form of tolmetin, developed to improve gastrointestinal tolerance while maintaining potent analgesic and antipyretic efficacy. The molecular formula of this compound is C23H25NO4S, and its unique Chemical Abstracts Service (CAS) registry number is 80917-62-4. This pharmaceutical agent functions primarily by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins that mediate pain, inflammation, and fever responses within the central and peripheral nervous systems. Originally synthesized for therapeutic applications in managing rheumatoid arthritis, osteoarthritis, and acute musculoskeletal disorders, Amtolmetin guacil has gained attention for its reduced incidence of gastric mucosal damage compared to traditional NSAIDs like tolmetin or aspirin. By undergoing rapid hydrolysis in the body, it releases the active metabolite tolmetin directly at the site of action, minimizing systemic irritation to the stomach lining. While historically manufactured in various global regions including Europe and Asia, production facilities in China have also contributed to the supply chain of this specific active pharmaceutical ingredient, ensuring availability for international markets seeking cost-effective yet high-quality pain management solutions. Clinically, this drug is indicated for the relief of mild to moderate pain, reduction of fever, and alleviation of inflammatory symptoms associated with chronic conditions. Its pharmacokinetic profile allows for effective dosing regimens that balance therapeutic benefit with safety, making it a preferred option for patients with sensitive gastrointestinal tracts who require long-term anti-inflammatory therapy. Despite the emergence of newer COX-2 selective inhibitors, Amtolmetin guacil remains a valuable tool in modern pharmacotherapy due to its established safety record and proven efficacy in diverse clinical settings. Manufacturers continue to refine synthesis processes to ensure purity and consistency, adhering to stringent international quality standards for export and domestic distribution.