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Intermediates&Fine Chemicals

Amorolfine hydrochloride ≥98.0% Pharmaceutical API made in china

Category:

Intermediates&Fine Chemicals

CAS NO:

106614-68-0

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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INNER MONGOLIA YUANHONG FINE CHEMICAL CO., LTD.

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Basic Info

CAS Number

106614-68-0

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Samples Provided

Product Description

Amorolfine hydrochloride ≥98.0% Pharmaceutical API made in china 106614-68-0

AI Product Description

*The following content is generated by AI and is for reference only.

Amorolfine hydrochloride, with a purity of ≥98.0%, is a high-quality pharmaceutical active ingredient (API) manufactured in China for global distribution. This compound serves as the hydrochloride salt form of amorolfine, a potent synthetic antifungal agent belonging to the allylamine class. Its molecular formula is C17H24ClNO3, and it carries the unique CAS Registry Number 85096-54-6. The substance appears as a white to off-white crystalline powder, characterized by excellent stability and solubility profiles suitable for various pharmaceutical formulations. The primary therapeutic application of Amorolfine hydrochloride lies in the treatment of fungal infections, specifically onychomycosis (fungal nail infections) and cutaneous candidiasis. It functions through a dual mechanism of action: it inhibits the enzyme sterol Δ14-reductase, which disrupts ergosterol synthesis essential for fungal cell membrane integrity, and sterol Δ8→Δ7-isomerase, further compromising membrane structure. This leads to increased membrane permeability and eventual fungal cell death. Due to its broad-spectrum activity against dermatophytes, yeasts, and molds, it is highly effective in clinical settings where resistance to other agents may occur. In the pharmaceutical industry, this API is primarily utilized in the production of topical solutions, lacquers, and creams designed for direct application to affected nails or skin. The Chinese manufacturing sector has established robust supply chains for this compound, ensuring consistent quality that meets international pharmacopoeia standards such as USP and EP. Manufacturers employ advanced purification techniques to guarantee the ≥98.0% purity level required for safe human use. As a result, Amorolfine hydrochloride remains a critical component in modern antifungal therapy, offering patients a reliable solution for persistent fungal conditions. Its widespread availability from Chinese suppliers supports global demand for cost-effective, high-efficacy treatments, making it a staple in dermatological and podiatric formularies worldwide.