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CAS NO:
18674-16-3
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Basic Info
CAS Number
18674-16-3
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Alisol A 24-acetate is a prominent bioactive triterpenoid saponin isolated primarily from the rhizomes of *Alisma plantago-aquatica*, a medicinal herb widely utilized in traditional Chinese medicine for treating dampness, edema, and metabolic disorders. With the molecular formula C32H50O7 and a CAS registry number of 1639-85-4, this compound belongs to the class of alisol-type oleanane triterpenoids characterized by an acetylated hydroxyl group at the C-24 position. Its chemical structure features a pentacyclic skeleton that contributes significantly to its potent pharmacological activities.
The primary applications of Alisol A 24-acetate focus on its diverse therapeutic potential in modern drug discovery and research. Extensive scientific studies have highlighted its strong anti-inflammatory properties, where it effectively inhibits key inflammatory mediators such as nitric oxide and pro-inflammatory cytokines in macrophage cells. Furthermore, this compound exhibits significant hepatoprotective effects, offering protection against liver injury induced by toxins like carbon tetrachloride or alcohol, making it a subject of interest for treating non-alcoholic fatty liver disease (NAFLD).
In the realm of oncology, emerging research suggests that Alisol A 24-acetate possesses promising anticancer capabilities. It has been observed to induce apoptosis and inhibit cell proliferation in various cancer cell lines, including hepatocellular carcinoma and breast cancer, often by modulating specific signaling pathways like PI3K/Akt. Additionally, its role in lipid metabolism regulation aids in reducing serum cholesterol and triglyceride levels, supporting its utility in managing metabolic syndrome. Due to these multifaceted biological activities, Alisol A 24-acetate serves not only as a valuable marker for quality control in herbal pharmaceuticals but also as a lead candidate for developing novel therapeutics targeting inflammation, liver diseases, and cancer. While currently used mainly in research settings, its natural origin and safety profile continue to drive investigations into its clinical translation for chronic disease management.
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