Product Description
Alarelin supplier Pharmaceutical API Polypeptide made in china 79561-22-1
AI Product Description
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Alarelin, a synthetic decapeptide analog of gonadotropin-releasing hormone (GnRH), is a highly specialized pharmaceutical API manufactured in China for veterinary and research applications. Its molecular formula is C53H76N14O10S2, with a molecular weight of approximately 1149.4 g/mol. The substance is identified by CAS number 86159-92-6. Structurally, Alarelin features a modified amino acid sequence compared to native GnRH, specifically replacing the L-histidine at position 2 with D-histidine and the glycine amide at the C-terminus with an ethylamide group. These modifications significantly enhance its metabolic stability and biological potency when administered subcutaneously or intramuscularly.
Primarily utilized in the livestock industry, Alarelin serves as a potent ovulation inducer and estrus synchronization agent for cattle, sheep, and goats. By stimulating the pituitary gland to release luteinizing hormone (LH) and follicle-stimulating hormone (FSH), it triggers the final maturation of ovarian follicles and subsequent ovulation. This mechanism is critical for improving reproductive efficiency in breeding programs, allowing farmers to precisely time insemination events and optimize herd management protocols. Unlike natural GnRH, which has a very short half-life, Alarelin provides a sustained response, making it a preferred choice for commercial agricultural operations seeking high conception rates.
In addition to veterinary use, Alarelin is frequently employed in scientific research to study the hypothalamic-pituitary-gonadal axis and reproductive endocrinology. Pharmaceutical suppliers in China produce this peptide using advanced solid-phase synthesis techniques, ensuring high purity levels suitable for both large-scale agricultural application and laboratory experimentation. While strictly regulated for animal use in many jurisdictions, its role in enhancing food production security remains significant globally. Users must adhere to local veterinary regulations regarding dosage and withdrawal periods to ensure food safety. As a cost-effective alternative to imported counterparts, Chinese-manufactured Alarelin offers competitive pricing without compromising efficacy, supporting the global demand for improved animal husbandry technologies.