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CAS NO:
24502-78-1
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Basic Info
CAS Number
24502-78-1
Pharmacopoeia
In-house Standards
Grade
Pharmaceutical Grade
Is Manufacturer
No
Product Description
please call me ,to know more
AI Product Description
*The following content is generated by AI and is for reference only.
Acetylshikonin is a prominent naphthoquinone derivative isolated primarily from the roots of *Lithospermum erythrorhizon* and related species within the Boraginaceae family. With the molecular formula C18H16O5 and a CAS registry number of 2453-07-4, this bioactive compound exhibits a distinctive deep red coloration and significant therapeutic potential. Structurally, it consists of an acetylated shikonin backbone, which enhances its lipophilicity compared to its parent compound, thereby improving cellular uptake and bioavailability in various biological assays.
The primary application of Acetylshikonin lies in the pharmaceutical and cosmetic industries due to its potent pharmacological properties. Extensive research has demonstrated its strong antimicrobial activity against a broad spectrum of pathogens, including both Gram-positive and Gram-negative bacteria, making it a candidate for developing novel topical antiseptics. Furthermore, it possesses notable anti-inflammatory effects by inhibiting pro-inflammatory cytokines and enzymes such as nitric oxide synthase, offering promise in treating inflammatory skin conditions. In the realm of oncology, studies suggest that Acetylshikonin induces apoptosis in cancer cells while exhibiting minimal toxicity toward normal cells, highlighting its potential as an anticancer agent.
Beyond medicine, the compound serves as a natural pigment in the cosmetic sector, utilized for its vibrant hue and antioxidant capabilities that help protect skin from oxidative stress. Its ability to promote wound healing by accelerating tissue regeneration adds further value to dermatological formulations. However, despite these advantages, challenges regarding extraction efficiency and stability remain areas of active investigation. As a result, ongoing research focuses on optimizing synthesis methods and exploring synergistic combinations with other herbal extracts to maximize efficacy. Overall, Acetylshikonin represents a versatile natural product with multifaceted applications ranging from infectious disease management to advanced skincare solutions, bridging traditional herbal medicine with modern biotechnology.
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