Chemical Name:Reserpine
- CAS No.50-55-5
- Molecular Formula:C33H40N2O9
- Formula Weight:608.689
Synonyms:3b,20a-Yohimban-16b-carboxylic acid, 18b-hydroxy-11,17a-dimethoxy- methyl ester 3,4,5-trimethoxybenzoate (ester)(8CI);11,17-Dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohi

*The following content is generated by AI and is for reference only.
Reserpine powder, identified by the CAS number 50-55-5 and widely recognized in pharmaceutical manufacturing with a purity level of 99% under Good Manufacturing Practice (GMP) standards, is a potent indole alkaloid derived from the roots of *Rauwolfia serpentina*. Its molecular formula is C33H40N2O9, reflecting a complex structure that includes multiple hydroxyl groups and an ester linkage essential for its biological activity. As a well-documented active pharmaceutical ingredient (API), Reserpine functions primarily as an antihypertensive agent by depleting catecholamines, serotonin, and dopamine from sympathetic nerve terminals, thereby reducing peripheral vascular resistance and lowering blood pressure. Historically significant, it remains a critical reference compound in research regarding neurotransmitter regulation and autonomic nervous system function.
Beyond its clinical applications in managing hypertension and certain psychiatric conditions associated with agitation or mania, high-purity Reserpine powder is extensively utilized in academic laboratories for pharmacological studies and biochemical assays. The availability of GMP-certified material ensures consistency, safety, and efficacy for both commercial drug formulation and rigorous scientific inquiry. Manufacturers adhere to strict quality control protocols, including detailed documentation via Drug Master Files (DMF), to guarantee that each batch meets international regulatory requirements. This certification is vital for pharmaceutical companies integrating Reserpine into generic formulations or developing new therapeutic combinations. Furthermore, the compound serves as a standard in analytical chemistry for validating chromatographic methods due to its distinct spectral properties. While newer agents have largely supplanted it in first-line therapy, Reserpine retains value in specific patient populations and resource-limited settings where cost-effectiveness is paramount. Its unique mechanism of action continues to provide insights into adrenergic transmission, making it an enduring subject of study in neuropharmacology. Overall, 99% pure Reserpine powder represents a cornerstone substance bridging traditional herbal medicine and modern evidence-based therapeutics, supported by robust supply chains ensuring global accessibility for medical and research communities alike.