Product Description
| Name |
Mannitol
|
EINECS |
201-770-2 |
| CAS No. |
87-78-5 |
Density |
1.596 g/cm3 |
| PSA |
121.38000 |
LogP |
-3.58540 |
| Solubility |
soluble |
Melting Point |
166-168oC |
| Formula |
C6H14O6 |
Boiling Point |
494.9 °C at 760 mmHg |
| Molecular Weight |
182.174 |
Flash Point |
292.5 °C |
| Transport Information |
N/A |
Appearance |
White fine powder |
AI Product Description
*The following content is generated by AI and is for reference only.
D-Mannitol, chemically identified by the CAS number 87-78-5, is a naturally occurring sugar alcohol widely recognized for its exceptional purity and versatility in global pharmaceutical and food industries. Its molecular formula is C6H14O6, reflecting a hexahydric alcohol structure derived from the reduction of mannose. This compound exists as a white, crystalline powder that is odorless, tasteless, and highly soluble in water, making it an ideal excipient for diverse formulations. The product described often carries "99% up GMP DMF" specifications, indicating it meets Grade A Good Manufacturing Practice standards with a Document File (DMF) on file with regulatory bodies like the FDA or EMA, ensuring rigorous quality control for human consumption.
In the pharmaceutical sector, D-Mannitol serves multiple critical functions. It is extensively utilized as a bulking agent and stabilizer in lyophilized injectable powders, such as antibiotics and vaccines, due to its ability to maintain structural integrity during freeze-drying. Furthermore, it acts as a renal protective agent; specifically, it is used to prevent acute kidney injury in patients undergoing chemotherapy or contrast imaging procedures. Its osmotic diuretic properties also make it valuable in managing intracranial pressure. Beyond medicine, the food industry leverages D-Mannitol as a low-calorie sweetener and anti-caking agent, particularly in sugar-free confectionery and chewing gums, where it provides bulk without contributing significantly to dental caries or blood glucose levels.
The distinction between D-Mannitol and its isomer, L-Mannitol or DL-Mannitol, is crucial for efficacy, as biological systems typically utilize the D-form. High-purity grades are essential for parenteral applications to minimize toxicity risks. With its non-hygroscopic nature and chemical stability, D-Mannitol remains a cornerstone ingredient in modern manufacturing. Whether formulated into tablets, capsules, or sterile solutions, this versatile polyol continues to support advancements in drug delivery systems and nutritional supplements globally, adhering to strict international safety and quality protocols.
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