Product Description
| Name |
Gentamicin
|
EINECS |
215-765-8 |
| CAS No. |
1403-66-3 |
Density |
1.3 g/cm3 |
| PSA |
627.17000 |
LogP |
-1.62550 |
| Solubility |
N/A |
Melting Point |
102-108° |
| Formula |
C21H43N5O7 |
Boiling Point |
669.4 °C at 760 mmHg |
| Molecular Weight |
477.60 |
Flash Point |
358.6 °C |
| Transport Information |
N/A |
AI Product Description
*The following content is generated by AI and is for reference only.
Gentamicin, identified by the CAS Registry Number 1403-66-3, is a widely utilized aminoglycoside antibiotic renowned for its potent bactericidal activity against a broad spectrum of Gram-negative bacteria and select Gram-positive organisms. The molecular formula of Gentamicin C1a, a primary component of the commercial mixture often referenced in pharmaceutical contexts, is C21H43N5O7, though the total mixture comprises several related congeners (C1, C1a, C2, C2a) with varying side chains that collectively define its efficacy profile. This compound operates by irreversibly binding to the 30S ribosomal subunit of susceptible bacteria, thereby inhibiting protein synthesis and leading to rapid cell death.
The product described as "99% up GMP DMF" signifies a high-purity grade manufactured under strict Good Manufacturing Practice (GMP) standards, ensuring consistency, safety, and quality suitable for human therapeutic applications. The inclusion of a Drug Master File (DMF) indicates that comprehensive data regarding the manufacturing process, quality control, and stability has been submitted to regulatory authorities like the FDA, facilitating faster approval for drug developers incorporating this ingredient into final formulations. Such high-grade Gentamicin is essential for treating serious infections including sepsis, pneumonia, urinary tract infections, and skin conditions caused by resistant pathogens. Furthermore, it serves as a critical reference standard in research laboratories for microbiological assays and susceptibility testing. Due to its potential nephrotoxicity and ototoxicity, precise dosing and monitoring are mandatory during clinical use. The availability of GMP-compliant material ensures that pharmaceutical manufacturers can produce sterile injectables, ophthalmic solutions, and topical creams with guaranteed potency and sterility, meeting global regulatory requirements for patient safety and therapeutic effectiveness in modern medicine.
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