Product Description
Betamethasone 21-phosphate disodium
- CAS No.151-73-5
- Molecular Formula:C22H28FNa2O8P
- Formula Weight:516.41
Synonyms:Pregna-1,4-diene-3,20-dione,9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11b,16b)- (9CI);Bentelan;Betamethasone 21-phosphate disodium salt;Betnes
AI Product Description
*The following content is generated by AI and is for reference only.
Betamethasone 21-phosphate disodium, identified by the CAS number 151-73-5, is a highly potent synthetic glucocorticoid derivative widely utilized in pharmaceutical and veterinary applications. Its molecular formula is C22H28Na2O9P, representing the sodium salt of betamethasone phosphate, which ensures superior water solubility compared to its parent compound. This chemical property makes it particularly suitable for injectable formulations, ophthalmic solutions, and topical preparations where rapid absorption and bioavailability are critical.
The primary clinical utility of Betamethasone 21-phosphate disodium lies in its potent anti-inflammatory, immunosuppressive, and antiproliferative effects. It functions by inhibiting the synthesis of multiple cytokines and inflammatory mediators, thereby effectively managing conditions such as severe allergic reactions, autoimmune disorders, rheumatoid arthritis, and dermatological inflammations like eczema or psoriasis. In ophthalmology, it is frequently employed to treat anterior segment inflammation following surgery or trauma. The "99% up GMP" designation indicates that this specific grade meets strict Good Manufacturing Practice standards with high purity, ensuring consistency, safety, and efficacy for human therapeutic use.
Beyond human medicine, this compound plays a significant role in veterinary pharmacology for treating inflammatory conditions in large and small animals. Its rapid onset of action allows for quick symptom relief in acute scenarios. However, due to its systemic potency, usage requires careful dosing to minimize potential side effects such as hyperglycemia, osteoporosis, or adrenal suppression associated with long-term corticosteroid therapy. The availability of this powder in high-purity GMP grades facilitates the development of stable dosage forms by pharmaceutical manufacturers globally. As a key intermediate and active pharmaceutical ingredient (API), Betamethasone 21-phosphate disodium remains a cornerstone in modern steroid therapy, bridging the gap between laboratory synthesis and clinical application through rigorous quality control measures defined by international regulatory bodies.
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