Product Description
Chemical Name: 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-butyl-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide (1:1), (1a,2b,4b,5a,7b)-
- CAS No.149-64-4
- Molecular Formula:C21H30NO4.Br
- Formula Weight:440.377
Synonyms:1aH,5aH-Tropanium, 8-butyl-6b,7b-epoxy-3a-hydroxy-,bromide, (-)-tropate (8CI);3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-butyl-7-[(2
AI Product Description
*The following content is generated by AI and is for reference only.
(-)-Scopolamine N-butyl bromide, commonly known as Hyoscine Butylbromide, is a potent anticholinergic and antispasmodic agent widely utilized in clinical medicine to relieve smooth muscle spasms. With the CAS Registry Number 149-64-4, this compound serves as a critical pharmaceutical intermediate and active ingredient in various formulations designed to treat gastrointestinal, biliary, and urinary tract colics. The molecule features a tropane alkaloid structure modified with a butyl group on the nitrogen atom, which significantly enhances its lipophilicity compared to natural scopolamine. This structural modification prevents the drug from easily crossing the blood-brain barrier, thereby minimizing central nervous system side effects such as drowsiness or confusion, while maintaining strong peripheral efficacy against visceral cramps.
The product is frequently marketed under trade names like Buscopan and is available in oral tablets, injectable solutions, and suppositories. Its primary mechanism of action involves the competitive antagonism of muscarinic acetylcholine receptors located on smooth muscle cells, leading to relaxation and reduced motility in affected organs. This makes it an essential tool for managing acute abdominal pain, dysmenorrhea, renal colic, and spastic conditions during diagnostic procedures like endoscopy. High-purity grades, often labeled as "99% up GMP DMF," indicate compliance with Good Manufacturing Practice standards and are submitted via Drug Master Files to regulatory agencies like the FDA or EMA. These certified materials ensure consistent quality, safety, and bioavailability for global pharmaceutical manufacturers producing generic or branded medications. Beyond therapeutic applications, (-)-scopolamine N-butyl bromide is also studied in research settings for its pharmacokinetic properties and receptor binding affinities. As a key component in international pharmacopoeias, it remains indispensable for emergency departments and gastroenterology clinics worldwide, offering rapid relief from severe pain associated with smooth muscle hyperactivity without compromising patient alertness.
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