*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>6-Maleimidocaproic acid</strong> is a heterobifunctional crosslinker featuring a maleimide group for thiol conjugation and a carboxyl group for amine coupling. Its molecular formula is C<sub>10</sub>H<sub>13</sub>NO<sub>4</sub> (CAS: 2879-45-0). The compound is synthesized via the reaction of 6-aminocaproic acid with maleic anhydride, enabling precise bioconjugation in antibody-drug conjugate manufacturing.</p>
<h3>Application</h3>
<ul>
<li>Bioconjugation: Site-specific attachment of payloads to antibodies for ADC development.</li>
<li>Protein Labeling: Modification of cysteine residues in research-grade proteins.</li>
<li>Diagnostic Reagents: Immobilization of enzymes on solid supports for immunoassays.</li>
</ul>
<h3>Precautions</h3>
<p>Store at -20°C under inert atmosphere to prevent hydrolysis. Avoid direct skin contact due to potential sensitization; use appropriate PPE. Not intended for direct clinical administration without formulation into approved pharmaceutical products.</p>