(4S,5R)-2-(4-methoxyphenyl)-4-phenyl-3,5-oxazolidinedicarboxylic acid 3-tert-butyl ester is an intermediate in organic synthesis and pharmaceutical intermediates, which can be used in laboratory research and development processes and chemical and pharmaceutical synthesis processes, mainly as a synthesis intermediate of docetaxel.
AI Product Description
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<h3>Overview</h3>
<p>This chiral oxazolidine derivative, <strong>(4S,5R)-3-(tert-butoxycarbonyl)-2-(4-methoxyphenyl)-4-phenyl-1,3-oxazolidine-5-carboxylic acid</strong>, serves as a critical stereodefined intermediate in asymmetric synthesis. Manufactured via enantioselective cyclization of amino alcohols and isocyanates, its molecular formula is C<sub>21</sub>H<sub>23</sub>NO<sub>6</sub>. CAS Registry Number: 907688-63-3.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical R&D:</strong> Chiral pool synthesis for beta-lactam antibiotics and protease inhibitors.</li>
<li><strong>Agrochemicals:</strong> Precursor for enantiomerically pure herbicides with reduced environmental impact.</li>
<li><strong>Material Science:</strong> Building block for advanced functional polymers requiring specific stereochemistry.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent hydrolysis of the Boc group. Personnel must utilize PPE including nitrile gloves and safety goggles due to potential skin irritation. Not intended for direct clinical use; strictly for industrial research and development purposes only.</p>