Product Description
4,6-Dichloropyrimidine Intermediate Pyrimidine made in china 1193-21-1
AI Product Description
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4,6-Dichloropyrimidine is a pivotal heterocyclic intermediate widely manufactured in China for the global pharmaceutical and agrochemical industries. With the molecular formula C₄H₂Cl₂N₂ and a CAS number of 1932-85-4, this white to off-white crystalline powder serves as a versatile building block in organic synthesis. Its chemical structure features two highly reactive chlorine atoms at the 4 and 6 positions of the pyrimidine ring, making it an ideal electrophilic substrate for nucleophilic substitution reactions. This reactivity allows chemists to easily replace the chlorine atoms with various functional groups, including amines, alcohols, thiols, and hydrazines, to construct complex molecular architectures efficiently.
In the pharmaceutical sector, 4,6-dichloropyrimidine is extensively utilized as a precursor for synthesizing kinase inhibitors, antiviral agents, and anticancer drugs. It plays a critical role in developing treatments for diseases such as hepatitis B and various cancers by enabling the formation of specific pyrimidine-based scaffolds essential for biological activity. Furthermore, in agriculture, derivatives of this compound are employed in the production of fungicides and herbicides that protect crops from pests and pathogens, contributing significantly to food security. The high purity and consistent quality of Chinese-manufactured batches have established the region as a reliable global supply hub for this chemical.
The compound is typically produced through chlorination processes involving uracil or similar precursors, adhering to strict environmental and safety standards. Due to its stability under standard storage conditions and ease of handling, it is shipped globally in bulk quantities to research laboratories and large-scale industrial facilities. As the demand for novel drug candidates and advanced agrochemicals continues to rise, 4,6-dichloropyrimidine remains a cornerstone intermediate in modern chemical manufacturing. Its ability to facilitate rapid structural diversification makes it indispensable for researchers seeking to optimize lead compounds and accelerate drug discovery pipelines. Consequently, this intermediate bridges the gap between basic chemical feedstocks and high-value therapeutic solutions, driving innovation across multiple scientific disciplines while supporting sustainable industrial growth in the chemical sector.