MF: C9H3F3N2S
Appearence:White to off-white powder
Usage: Used in biochemical reagents and peptide synthesis
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>4-Isothiocyanato-2-(trifluoromethyl)benzonitrile</strong> (CAS: 100678-59-5) is a specialized heterocyclic intermediate defined by its reactive isothiocyanate and trifluoromethyl groups. Synthesized via nitration followed by halogen exchange and thiophosgene reaction, it serves as a critical building block for medicinal chemistry.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical synthesis of kinase inhibitors and covalent ligands.</li>
<li>Construction of heterocyclic scaffolds in agrochemical research.</li>
<li>Preparation of radiolabeled tracers for diagnostic imaging.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly store under inert atmosphere at -20°C to prevent hydrolysis. Personnel must utilize full PPE due to potential toxicity and skin sensitization risks associated with isothiocyanate moieties.</p>