4-[FLUORO(DIMETHYL)SILYL]BUTANENITRILE化学性质沸点:185.5±23.0°C(Predicted)密度:0.895±0.06g/cm3(Predicted)蒸气压:7.9hPaat20℃形态:LiquiChemicalbookdInChI:InChI=1S/C6H12FNSi/c1-9(2,7)6-4-3-5-8/h3-4,6H2,1-2H3InChIKey:RZHGQUVEZKATLV-UHFFFAOYSA-NSMILES:C(#N)CCC[Si](F)(C)C
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4-[Fluoro(dimethyl)silyl]butanenitrile is a specialized organosilicon compound widely utilized in advanced chemical synthesis and materials science. With the molecular formula C6H12FNSi, this molecule combines the reactivity of a nitrile group with the unique properties of a silyl moiety bearing a fluorine atom and two methyl groups. Its precise Chemical Abstracts Service (CAS) registry number is 138970-85-9, which serves as its unique identifier for regulatory compliance and inventory management across global supply chains.
The primary application of this compound lies in the pharmaceutical industry, where it acts as a crucial intermediate for synthesizing complex heterocyclic structures and bioactive molecules. The presence of the nitrile functional group allows for versatile transformations into amides, amines, or carboxylic acids through standard hydrolysis or reduction protocols, while the silyl-fluoride unit offers distinct advantages in cross-coupling reactions and protecting group strategies. In the field of organic electronics, this substance is increasingly explored for the development of novel silicon-containing polymers and liquid crystals. The specific arrangement of the dimethylsilyl and fluoro substituents enhances thermal stability and modifies dielectric properties, making it valuable for producing high-performance insulating materials and semiconductor precursors.
Furthermore, researchers utilize 4-[fluoro(dimethyl)silyl]butanenitrile in the study of silane coupling agents designed to improve adhesion between inorganic substrates and organic matrices. Its relatively short carbon chain ensures efficient transport of the silyl functionality to reaction sites without excessive steric hindrance. Safety data indicates that like many organosilicon nitriles, it requires careful handling to avoid exposure to moisture, which could potentially lead to the release of toxic hydrogen cyanide or corrosive hydrofluoric acid under extreme conditions. Storage should be conducted in a cool, dry environment within sealed containers to maintain purity and prevent degradation. As the demand for functionalized silicon compounds grows in nanotechnology and drug discovery, this specific derivative stands out as a versatile building block for creating next-generation materials with tailored physical and chemical characteristics.