*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>(4-chloro-2-fluorophenyl)boronic acid is a versatile organoboron intermediate primarily synthesized via halogen-metal exchange or direct borylation of 1-chloro-4-fluoro-2-bromobenzene. The compound features the molecular formula <strong>C6H5BClFO</strong> and carries CAS number <strong>100977-38-8</strong>. It serves as a critical coupling partner in palladium-catalyzed Suzuki-Miyaura reactions.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceuticals:</strong> Synthesis of kinase inhibitors and antiviral agents.</li>
<li><strong>Agrichemicals:</strong> Production of novel herbicides and fungicides.</li>
<li><strong>Materials Science:</strong> Fabrication of organic light-emitting diodes (OLEDs).</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at temperatures below -20°C to prevent oxidation. Personnel must utilize appropriate respiratory protection and nitrile gloves, as the substance may cause severe skin irritation and respiratory sensitization upon exposure.</p>