苯并二唑-4-甲醛化学性质熔点:100-102°C沸点:277°C密度:1.417闪点:121°C储存条件:Inertatmosphere,2-8°C溶解度:DichloromethChemicalbookane(Slightly),Chloroform(Slightly),Methanol(Slightly)形态:Solid酸度系数(pKa):-1.86±0.45(Predicted)
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4-Benzofurazancarboxaldehyde is a specialized heterocyclic organic compound widely utilized in medicinal chemistry and materials science research. Its molecular formula is C8H5NO3, reflecting a structure composed of a benzofurazan core fused with an aldehyde functional group at the fourth position. The compound is cataloged under CAS Registry Number 26170-93-8, ensuring precise identification for laboratory procurement and safety documentation. This molecule serves as a critical synthetic intermediate, particularly valued for its reactive aldehyde moiety which facilitates diverse chemical transformations such as condensation reactions, Schiff base formation, and nucleophilic additions.
In pharmaceutical development, 4-Benzofurazancarboxaldehyde acts as a precursor for synthesizing complex heterocyclic scaffolds, including fluorophores, dyes, and potential bioactive agents targeting specific enzymatic pathways. Researchers often employ it to construct derivatives with enhanced optical properties or improved biological activity, making it indispensable in the discovery of new antibiotics, anticancer drugs, and anti-inflammatory compounds. Furthermore, the unique electronic characteristics of the benzofurazan ring system contribute to the stability and fluorescence of resulting products, supporting applications in optoelectronic materials and sensor technology.
Safety protocols dictate that this substance should be handled with care due to potential irritant properties. Standard laboratory practices require the use of personal protective equipment, including gloves and goggles, within a well-ventilated fume hood. Storage conditions must maintain a cool, dry environment away from incompatible oxidizers to prevent degradation or hazardous reactions. While not typically available as a bulk commodity, high-purity grades are accessible through specialized chemical suppliers catering to academic and industrial research sectors. As demand grows for advanced functional materials and novel therapeutic candidates, the role of 4-Benzofurazancarboxaldehyde remains pivotal in bridging fundamental organic synthesis with practical application in cutting-edge scientific fields. Its versatility underscores the importance of heterocyclic chemistry in modern innovation, driving continuous exploration into new molecular architectures with tailored properties for future technological advancements.