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(3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione

Category:

Other Intermediates

CAS NO:

14805-29-9

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Jinan Xinnuo Pharmaceutical Co., Ltd

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Basic Info

CAS Number

14805-29-9

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Samples Provided

Product Description

Cigna Qingdao is mainly engaged in the intermediates of febuxostatin, ceflothrin, eprazole, flubiprofen, phenalidone, tovaptan, rivaroxaban and Avanafil, terbinafine intermediates, thioacetamide and thiophene and their derivatives.

AI Product Description

*The following content is generated by AI and is for reference only.

(3aR,4S,7R,7aS)-4,7-Methano-1H-isoindole-1,3(2H)-dione is a sophisticated chiral organic compound belonging to the family of bicyclic imide derivatives. Its specific stereochemical configuration, denoted by the (3aR,4S,7R,7aS) nomenclature, distinguishes it from other geometric isomers, granting it unique three-dimensional structural properties essential for high-precision applications in medicinal chemistry and asymmetric synthesis. While commercial catalogs often list this substance under generic or specialized identifiers rather than a widely publicized CAS number due to its niche nature as an advanced intermediate, its molecular framework is defined by a fused isoindole core bridged by a methylene group, resulting in the chemical formula C9H7NO2. This rigid bicyclic architecture serves as a critical scaffold in the development of novel pharmaceutical agents, particularly those targeting neurological disorders or acting as enzyme inhibitors. The primary utility of this enantiomerically pure compound lies in its role as a building block for complex drug discovery programs. Researchers utilize its distinct spatial arrangement to construct libraries of bioactive molecules where stereochemistry dictates biological activity and pharmacokinetic profiles. The presence of the imide functionality offers versatile sites for further functionalization, allowing chemists to attach various substituents that modulate solubility, binding affinity, and metabolic stability. In materials science, similar methano-isoindole structures are occasionally explored for their potential in creating advanced polymers with enhanced thermal resistance or specific optical properties, although pharmaceutical applications remain the dominant focus. Due to its chirality, strict quality control measures are required during synthesis to ensure the correct stereoisomer is obtained, as the wrong configuration could render the molecule biologically inactive or even toxic. Consequently, this compound represents a vital component in the toolkit of synthetic organic chemists aiming to solve complex therapeutic challenges through precise molecular engineering.