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Other Specialized Reagents

3-[(1S)-1-(Dimethylamino)ethyl]phenol

Category:

Other Specialized Reagents

CAS NO:

139306-10-8

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

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Hunan HuaTeng Pharmaceutical Co., Ltd.

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Basic Info

CAS Number

139306-10-8

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Product Description

Huateng Pharma, a global supplier of pharmaceutical intermediates, PEG derivatives and other chemical products, offers CAS NO.139306-10-8 for your requirements of R&D, evaluation, pilots and commercial along with supportive technical package required for evaluation.

Application: Intermediate of anti-senile dementia drug Rivastigmine.

AI Product Description

*The following content is generated by AI and is for reference only.

3-[(1S)-1-(Dimethylamino)ethyl]phenol is a specialized chiral organic compound featuring a phenolic hydroxyl group and a dimethylaminoethyl side chain attached at the meta position of the benzene ring. Its stereochemistry is defined by the (1S) configuration, which imparts specific optical activity and biological relevance crucial for pharmaceutical applications. The molecular formula of this substance is C10H15NO, with a precise molecular weight of approximately 165.23 g/mol. While exact CAS registry numbers can vary slightly depending on specific salt forms or purity grades, the base structure typically corresponds to distinct identifiers used in chemical databases for enantiomerically pure intermediates. This compound serves primarily as a critical building block in medicinal chemistry research, particularly in the synthesis of beta-adrenergic receptor modulators and other bioactive agents. The presence of both the electron-rich phenol moiety and the basic amine functionality allows for versatile chemical modifications, enabling researchers to tailor pharmacokinetic properties such as solubility and metabolic stability. In drug discovery pipelines, this chiral intermediate is often employed to construct complex heterocyclic systems or to probe structure-activity relationships (SAR) within adrenergic ligand families. The (1S) enantiomer is frequently preferred over its racemic mixture due to the potential for higher binding affinity and reduced off-target effects in therapeutic contexts. Beyond direct pharmaceutical synthesis, it finds utility in academic studies investigating stereoselective reactions and enzymatic pathways involving catechol-like structures. Industrial applications remain niche, focusing on high-value fine chemical production rather than bulk commodity markets. Safety handling requires standard precautions for amines and phenols, including protection against skin irritation and inhalation risks. Storage conditions should maintain low temperatures and inert atmospheres to prevent oxidation of the phenolic group or degradation of the amine functionality. As demand for targeted therapies grows, compounds like 3-[(1S)-1-(Dimethylamino)ethyl]phenol will likely see increased utilization in developing next-generation therapeutics for cardiovascular and neurological disorders. Researchers must ensure strict adherence to regulatory guidelines when sourcing or synthesizing this material to guarantee enantiomeric purity and reproducibility in experimental outcomes.