Product Description
熔点:42-44°C(lit.)沸点:153°C23mmHg(lit.)密度:1,284g/cm3堆积密度:350kg/m3蒸气密度:5.2(vsair)折射率:1.5800(estimate)闪点:>230°F储存条件:Storebelow+30°C.溶解度:Chloroform(Slightly),EthylAcetate(Slightly)形态:CrystallinePowder,Needlesand/orCChemicalbookhunks颜色:Yellow水溶解性:Insolubleinwater.敏感性:AirSensitiveMerck:14,6586BRN:742624LogP:1.74at25℃CAS数据库:552-89-6(CASDataBaseReference)NIST化学物质信息:Benzaldehyde,2-nitro-(552-89-6)EPA化学物质信息:Benzaldehyde,2-nitro-(552-89-6)
AI Product Description
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2-Nitrobenzaldehyde, chemically designated as 2-nitrobenzenecarbaldehyde, is a vital organic intermediate widely utilized in the pharmaceutical and agrochemical industries. With the molecular formula C7H5NO3 and a molecular weight of approximately 151.12 g/mol, this compound presents as pale yellow to orange crystalline solids or needles. Its distinctive chemical structure features an aldehyde group positioned ortho to a nitro group on the benzene ring, creating unique reactivity patterns essential for complex synthesis. The primary CAS Registry Number for 2-Nitrobenzaldehyde is 552-89-6, which serves as its universal identifier in global chemical databases and regulatory frameworks.
This substance plays a pivotal role as a building block in the manufacture of various heterocyclic compounds, particularly quinolines, isoquinolines, and indoles. These heterocycles are fundamental scaffolds found in numerous active pharmaceutical ingredients (APIs) used to treat cardiovascular diseases, infections, and neurological disorders. In the agricultural sector, it serves as a precursor for synthesizing specific fungicides and herbicides that protect crops from pathogens while ensuring food security. Furthermore, 2-Nitrobenzaldehyde is frequently employed in the production of dyes and pigments due to its ability to undergo condensation reactions with active methylene compounds, yielding highly conjugated systems with vibrant colors.
From a safety perspective, handling this material requires standard laboratory precautions. It should be stored in a cool, dry, and well-ventilated area away from strong oxidizers and reducing agents. As an aromatic aldehyde, it may cause skin irritation or sensitization upon prolonged contact, necessitating the use of appropriate personal protective equipment such as gloves and goggles during manipulation. While not classified as extremely hazardous under normal conditions, proper ventilation is crucial to avoid inhalation of dust or vapors. Its solubility profile allows it to dissolve readily in common organic solvents like ethanol, ether, and chloroform, facilitating its integration into diverse synthetic protocols. Overall, 2-Nitrobenzaldehyde remains an indispensable reagent in modern organic chemistry, bridging the gap between basic petrochemical derivatives and high-value functional materials.
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