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Other Specialized Reagents

2-Fluoro-3-oxo-pentanoicacidmethyl ester

Category:

Other Specialized Reagents

CAS NO:

180287-02-9

Standard:

In-house Standards,

Price Range:

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North America,Western Europe,Eastern Europe,Asia

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Hunan HuaTeng Pharmaceutical Co., Ltd.

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Basic Info

CAS Number

180287-02-9

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

Product Description

Huateng Pharma, a professional pharmaceutical intermediate supplier, provides Voriconazole intermediate CAS No. 180287-02-9 2-Fluoro-3-oxo-pentanoicacidmethyl ester for your requirements of R&D, evaluation, pilots and commercial along with supportive technical package required for evaluation.

AI Product Description

*The following content is generated by AI and is for reference only.

2-Fluoro-3-oxopentanoic acid methyl ester is a specialized organic compound primarily utilized as a sophisticated building block in modern medicinal chemistry and fine chemical synthesis. With the molecular formula C6H9FO3, this molecule features a unique combination of a fluorinated alkyl chain, a ketone functionality, and an ester group, making it highly reactive and versatile for various synthetic transformations. The presence of the fluorine atom at the alpha-position relative to the carbonyl group significantly influences the electronic properties and metabolic stability of derivatives synthesized from this precursor, a critical factor in the development of novel pharmaceutical agents. The primary application of 2-fluoro-3-oxopentanoic acid methyl ester lies in the construction of complex heterocyclic systems and fluorinated bioisosteres. Researchers frequently employ this reagent in nucleophilic addition reactions, condensation processes, and cyclization protocols to generate substituted pyridines, pyrroles, and other nitrogen-containing rings that are essential scaffolds in drug discovery. Its role as a fluorinated acetoacetic ester analog allows chemists to introduce fluorine atoms into specific positions of target molecules, thereby modulating lipophilicity, binding affinity, and pharmacokinetic profiles without drastically altering the steric bulk of the parent structure. While specific CAS registry numbers for this exact isomer may vary depending on the precise stereochemistry or supplier cataloging conventions, it is generally recognized within the chemical industry as a key intermediate for creating advanced therapeutic candidates. It is particularly valuable in the synthesis of antiviral drugs, anticancer agents, and central nervous system therapeutics where fluorine incorporation is known to enhance biological activity. Due to its sensitivity to moisture and potential reactivity with strong bases, proper handling under inert atmospheres is recommended during laboratory procedures. As the demand for fluorinated compounds continues to rise in the pharmaceutical sector, 2-fluoro-3-oxopentanoic acid methyl ester remains an indispensable tool for synthetic chemists aiming to innovate next-generation medicines with improved efficacy and safety profiles.