As an important intermediate in the synthesis of new and efficient fluorine-containing pesticides and pharmaceuticals, derivatives of difluoroaromatic hydrocarbons have a very broad application value. The study of its synthesis method is one of the hot chemical book points of organic synthesis at present, which has attracted widespread attention. 2-Chloro-2',5'-difluoroacetophenone is an important organic synthesis intermediate and is widely used in pharmaceutical, pesticide and chemical industries.