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<h3>Overview</h3>
<p><strong>2-Boc-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid</strong> (CAS 158793-88-1) is a protected heterocyclic building block used in peptide synthesis. Its molecular formula is C<sub>15</sub>H<sub>19</sub>NO<sub>4</sub>. The compound features a tert-butoxycarbonyl group protecting the amine functionality on the tetrahydroisoquinoline scaffold.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical R&D:</strong> Serves as a key intermediate for synthesizing bioactive alkaloids and peptidomimetics.</li>
<li><strong>Medicinal Chemistry:</strong> Utilized in library construction for high-throughput screening of drug candidates.</li>
<li><strong>Organic Synthesis:</strong> Acts as a chiral pool precursor for complex nitrogen-containing heterocycles.</li>
</ul>
<h3>Precautions</h3>
<p>Store under inert atmosphere at -20°C to prevent hydrolysis. Avoid skin contact and inhalation; use appropriate PPE during handling. Not approved for direct clinical administration without further purification and formulation.</p>