Huateng Pharma, a global supplier of pharmaceutical intermediates, PEG derivatives and other chemical products, offers CAS NO.1030825-20-7 for your requirements of R&D, evaluation, pilots and commercial along with supportive technical package required for evaluation.
Application: It is an intermediate of Canogliflozin, a medication used to treat type 2 diabetes.
*The following content is generated by AI and is for reference only.
2-[(5-Bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene is a specialized organic compound primarily utilized in the fields of medicinal chemistry and materials science. With the molecular formula C19H14BrFOS, this molecule features a central thiophene ring substituted with a 4-fluorophenyl group at the 5-position and a (5-bromo-2-methylphenyl)methyl moiety at the 2-position. Its precise chemical identity corresponds to CAS Registry Number 1376849-06-3, ensuring accurate identification for research and procurement purposes.
The synthesis of this compound typically involves cross-coupling reactions, such as Suzuki-Miyaura or Stille couplings, which are critical for constructing complex heterocyclic architectures. The presence of the bromine atom serves as a versatile synthetic handle, allowing for further functionalization through palladium-catalyzed transformations. This structural flexibility makes it an invaluable intermediate in the development of novel pharmaceutical agents, particularly those targeting neurological disorders, oncology, and inflammatory conditions. Researchers often employ such thiophene derivatives to explore structure-activity relationships (SAR), aiming to optimize drug potency and selectivity while minimizing toxicity.
Beyond its potential biomedical applications, this molecule also holds significance in the realm of organic electronics. Thiophene-based compounds are renowned for their excellent charge transport properties and thermal stability, making them ideal candidates for use in organic light-emitting diodes (OLEDs), organic field-effect transistors (OFETs), and solar cells. The specific substitution pattern of this derivative likely influences its electronic band gap and photophysical characteristics, offering unique opportunities for tuning material performance. Consequently, it serves as a key building block for designing next-generation semiconductors with enhanced efficiency.
Due to its complexity and specific substituents, this product is generally not available as a bulk commodity but rather as a custom-synthesized reagent for laboratory-scale investigations. Strict adherence to safety protocols is required during handling, as many organobromine compounds can be irritants or toxic upon exposure. Laboratories engaged in advanced chemical research should consult detailed safety data sheets before usage. Overall, 2-[(5-bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene represents a sophisticated tool for scientists pushing the boundaries of molecular design in both therapeutic and technological domains.