*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>(1R,2S)-2-(3,4-difluorophenyl)cyclopropanecarboxamide is a specialized chiral intermediate primarily utilized in the synthesis of advanced pharmaceutical agents. The core manufacturing process involves asymmetric cyclopropanation followed by precise amide coupling to ensure stereochemical integrity. Its molecular formula is C<sub>10</sub>H<sub>9</sub>F<sub>2</sub>NO and it is identified by CAS No. 136785-35-6.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Serves as a critical building block for developing non-steroidal anti-inflammatory drugs (NSAIDs) and cardiovascular therapeutics.</li>
<li><strong>Research & Development:</strong> Employed in medicinal chemistry labs for structure-activity relationship (SAR) studies to optimize drug potency and metabolic stability.</li>
</ul>
<h3>Precautions</h3>
<ul>
<li><strong>Safety:</strong> Handle with appropriate PPE; avoid inhalation of dust or direct skin contact due to potential irritant properties.</li>
<li><strong>Storage:</strong> Store in a cool, dry, well-ventilated area away from strong oxidizing agents and moisture to maintain chemical stability.</li>
</ul>