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(1R,2R)-1,2-CYCLOHEXANEDIMETHANOL

Category:

Other Intermediates

CAS NO:

65376-05-8

Standard:

In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Jinan Xinnuo Pharmaceutical Co., Ltd

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Basic Info

CAS Number

65376-05-8

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Samples Provided

Product Description

Cigna Qingdao is mainly engaged in the intermediates of febuxostatin, ceflothrin, eprazole, flubiprofen, phenalidone, tovaptan, rivaroxaban and Avanafil, terbinafine intermediates, thioacetamide and thiophene and their derivatives.

AI Product Description

*The following content is generated by AI and is for reference only.

(1R,2R)-1,2-Cyclohexanedimethanol is a specialized chiral diol widely recognized in the fine chemical and pharmaceutical industries for its unique stereochemical configuration. With the molecular formula C8H16O2 and the CAS number 14379-09-6, this compound serves as a critical building block for synthesizing complex organic structures. The molecule consists of a cyclohexane ring substituted with two hydroxymethyl groups at positions 1 and 2, arranged in a specific trans-diaxial or diequatorial conformation that defines its (1R,2R) chirality. This precise three-dimensional arrangement distinguishes it from its racemic counterpart or other stereoisomers, granting it distinct physical and chemical properties essential for asymmetric synthesis. In industrial applications, (1R,2R)-1,2-cyclohexanedimethanol is primarily utilized as an intermediate in the production of high-performance polymers and resins. It acts as a valuable co-monomer in the formulation of polyesters and polyurethanes, where its rigid cyclic structure enhances thermal stability, mechanical strength, and UV resistance in the final material. Furthermore, due to its chiral nature, it plays an indispensable role in the pharmaceutical sector as a chiral pool reagent. Chemists employ it to construct enantiomerically pure active pharmaceutical ingredients (APIs), ensuring the biological efficacy and safety of drugs by minimizing unwanted side effects associated with incorrect stereoisomers. Its utility extends into agrochemicals and liquid crystal displays, where optical purity is paramount for device performance. The synthesis of this compound typically involves the asymmetric hydrogenation of dimethyl terephthalate derivatives or the enzymatic resolution of racemic mixtures, processes that demand high precision to maintain optical purity. Handling requires standard laboratory precautions, as it is generally stable under ambient conditions but should be stored away from strong oxidizing agents. As the demand for sustainable and high-efficiency materials grows, (1R,2R)-1,2-cyclohexanedimethanol remains a cornerstone in advanced material science, bridging the gap between fundamental organic chemistry and practical engineering solutions. Its versatility ensures continued relevance across diverse technological sectors, driving innovation in polymer design and drug discovery.