1H-Pyrazole-1-carboxamidine hydrochloride is an organic intermediate that can be obtained by one-step reaction loop of aminoguanidine carbonate and 1,1,3,3-tetramethoxypropane, or by one-step reaction of imidazole and cyanamide.
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<h3>Overview</h3>
<p><strong>1H-Pyrazole-1-carboxamidine hydrochloride</strong> is a key heterocyclic intermediate synthesized via the reaction of 1H-pyrazole with formamidine acetate followed by acidification. It serves as a vital scaffold in medicinal chemistry, featuring molecular formula C4H7ClN4 and CAS No. 26093-58-9.</p>
<h3>Application</h3>
<ul>
<li>Pharmaceutical synthesis: Precursor for antiviral and anticancer agents.</li>
<li>Agricultural chemicals: Intermediate for novel fungicides and herbicides.</li>
<li>Material science: Building block for functional organic ligands.</li>
</ul>
<h3>Precautions</h3>
<p>Store in a cool, dry place under inert atmosphere to prevent hydrolysis. Use appropriate PPE during handling due to potential skin irritation; avoid inhalation of dust or vapors.</p>