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Prophylactic Biological Products

1-Fluoronaphthalene

Category:

Prophylactic Biological Products

CAS NO:

321-38-0

Standard:

In-house Standards,

Price Range:

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North America,Central/South America,Western Europe,Eastern Europe,Australasia,Eastern Europe,Australasia,Asia,Middle East,Africa

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Basic Info

CAS Number

321-38-0

Pharmacopoeia

In-house Standards

Grade

Pharmaceutical Grade

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Product Description

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AI Product Description

*The following content is generated by AI and is for reference only.

1-Fluoronaphthalene is a specialized organic fluorinated compound characterized by a naphthalene ring system substituted with a single fluorine atom at the first position. With the chemical formula C10H7F and the CAS Registry Number 364-58-9, this substance belongs to the class of aromatic fluorides. It appears as a colorless to pale yellow liquid or low-melting solid under standard conditions, possessing distinct physicochemical properties that differentiate it from its non-fluorinated parent compound, 1-naphthyl derivatives. The introduction of the highly electronegative fluorine atom significantly alters the electronic distribution within the aromatic ring, enhancing metabolic stability and lipophilicity in various biological contexts. Primarily utilized in the pharmaceutical and agrochemical industries, 1-Fluoronaphthalene serves as a critical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and bioactive molecules. Its unique reactivity allows for efficient nucleophilic aromatic substitution reactions, facilitating the construction of diverse heterocyclic frameworks essential for drug discovery. Researchers frequently employ this compound as a building block to develop novel therapeutics targeting specific enzymatic pathways, leveraging the "fluorine effect" to improve pharmacokinetic profiles such as oral bioavailability and half-life. Additionally, it finds applications in materials science, where it contributes to the development of advanced functional polymers and liquid crystals with tailored optical and electrical characteristics. In academic research, 1-Fluoronaphthalene acts as a model substrate for studying reaction mechanisms involving organofluorine chemistry and understanding substituent effects on aromatic systems. While not typically used as a standalone commercial product due to its high cost and specialized nature, its role as a precursor remains indispensable in fine chemical manufacturing. Handling requires adherence to strict safety protocols, as with most aromatic halides, ensuring proper ventilation and protective equipment are used during synthesis and processing. As the demand for fluorinated compounds in modern medicine and technology continues to rise, 1-Fluoronaphthalene stands out as a versatile and valuable component in the global chemical supply chain, bridging fundamental organic synthesis with practical industrial applications.