Natural selective fluorinating agents are in many ways the ideal "probe" for physiological systems. Due to the presence of trifluoromethyl moieties in the molecule, the lipophilicity of the molecule is increased and the transport effect of fluorinated molecules in the physiological system is improved. The role of fluorinated Chemicalbook substances is thought to inhibit, alternate and enhance normal physiological processes. The vast majority of fluorinating agents generally have high toxicity and high reactivity, and a lot of work in the field of organofluorine chemistry often needs to be carried out in laboratories with special conditions.