Huateng Pharmaceutical, a global supplier of pharmaceutical Intermediates, offers Irbesartan Intermediates 1-Amino-1-cyclopentanecarboxamide (CAS NO. 17193-28-1) for your requirements of R&D, evaluation, pilots and commercial along with supportive technical package required for evaluation.
Application: An intermediate of Irbesartan (Avapro) (I751000).
*The following content is generated by AI and is for reference only.
1-Amino-1-cyclopentanecarboxamide is a specialized organic compound characterized by a cyclopentane ring substituted with both an amino group and a carboxamide moiety at the same carbon position. This unique structural arrangement classifies it as a cyclic alpha-amino acid derivative, making it a valuable building block in medicinal chemistry and peptide synthesis. The molecular formula for this compound is C6H12N2O, and its specific identity is often tracked via CAS Registry Number 14387-50-9, though variations may exist depending on salt forms or stereochemistry.
The primary utility of 1-Amino-1-cyclopentanecarboxamide lies in its application as a chiral auxiliary or a scaffold for constructing complex heterocyclic systems. Due to the presence of the secondary amine and the primary amide functionality, it serves as a versatile intermediate for synthesizing bioactive molecules, including potential pharmaceutical agents targeting neurological disorders, anti-inflammatory drugs, and novel enzyme inhibitors. Researchers frequently employ this molecule to introduce conformational constraints into peptide chains, thereby enhancing metabolic stability and binding affinity against biological receptors. Its rigid cyclopentane backbone restricts rotational freedom, which can significantly influence the pharmacokinetic properties of derived compounds.
Furthermore, this substance finds relevance in materials science, where it acts as a precursor for developing functional polymers with specific thermal or mechanical characteristics. In academic research settings, it facilitates studies on reaction mechanisms involving nucleophilic substitution and cyclization reactions. While not a commodity chemical, its niche status makes it essential for high-value synthetic pathways requiring precise stereochemical control. Safety data indicates standard precautions for handling amines and amides, necessitating proper ventilation and protective equipment to avoid skin irritation or inhalation risks. As the demand for targeted drug discovery grows, derivatives of 1-Amino-1-cyclopentanecarboxamide are expected to play an increasingly critical role in advancing therapeutic innovations across various medical disciplines.