*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride</strong> (EDC·HCl, CAS <strong>25952-53-8</strong>) is a water-soluble zero-length crosslinking reagent. It activates carboxyl groups to form unstable O-acylisourea intermediates for peptide coupling and bioconjugation.</p>
<h3>Application</h3>
<ul>
<li>Peptide synthesis: Amide bond formation without spacer arms.</li>
<li>Protein conjugation: Linking antigens to carriers or enzymes.</li>
<li>Biomaterials: Surface modification of polymers via carboxyl activation.</li>
</ul>
<h3>Precautions</h3>
<p>Store at 2–8°C in a dry environment. Avoid inhalation and skin contact; use appropriate PPE. Not intended for direct clinical administration as a therapeutic agent.</p>