What is Sucralose?
Sucralose is a zero-calorie artificial sweetener that is made in a multistep chemical process involving the replacement of hydroxyl groups with chlorine atoms.
Definition
A white crystalline powder derived from sucrose is sweeter than sucrose.
Chemical & physical features
IUPAC name: (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol
Synonyms: Trichlorogalacto-sucrose, EINECS 259-952-2
CAS: 56038-13-2
Molecular formula: C12H19Cl3O8
Molecular weight: 397.6
Form: Crystalline powder
Color: White-to-off-white
Solubility: Completely soluble in water, methanol, and ethanol
Brand names
Splenda
Aspasvit
Acucar Light
Trichlorosucrose
Sucralose forms and specifications
Sucralose is available in two forms i.e. granulated and powdered. The granulated version is often mixed with fillers to provide an alternative to table sugar. On the other hand, the powdered form of sucralose contains as much as 90% bulking agents e.g. maltodextrin.
Sucralose powder 99%
This refers to the sucralose active pharmaceutical ingredient that is commonly used in products like beverages, fruit juices, seasoning milk, pharmaceutical, and certain other healthcare products. Sucralose is deemed to be 600-650 times sweeter than table sugar. In terms of taste, sucralose is in the same league as table sugar. The same stands true for resistivity to external factors like high temperature, acidic environment. This is important because it means that the powder can be used in all kinds of foods and medicines. Sucralose is highly miscible in water. There are no safety concerns associated with sucralose consumption. Pure sucralose powder that is 99% pure is usually available in packaging of various weights.
Sucralose vs stevia
Stevia is another table sugar alternative that is made by concentrating the sweet compounds found in some fruits and plant leaves. Stevia is commonly used in sports drinks, sodas and is available in small sachet packs as well. These packs are super handy in case you want to add a dash of stevia to your cup of evening tea or coffee. Apart from the difference in the manner in which these two table sugar alternatives are prepared, another key difference lies in the usage. Sucralose is an ideal choice for cooking and baking while the extra sweet nature of stevia makes it an ideal choice for drinks. Because sucralose’s chlorine atoms can be absorbed by the body which can attack the good bacteria in your body, stevia is considered to be the safer option among the two. Stevia is deemed to be 30-150 times sweeter as compared to natural sugar and is both heat and pH-stable.
Sucralose vs aspartame
Aspartame refers to a sugar substitute that contains two amino acids namely aspartic acid and phenylalanine. Aspartame was given the FDA approval in the year 1981, the nutritive sweetener offers four calories per gram. Aspartame is 200 times sweeter than sugar and contains fillers like maltodextrin which serve the purpose of mellowing its intense sweetness. This table sugar alternative is used in chewing gum, cereals, beverages, instant coffees, and certain other food items. Its molecular formula is C14H18N2O5 while its molecular mass is 294.3 g/mol. While sucralose is commonly sold under the brand name Splenda, aspartame is popularly sold as NutraSweet or Equal.
Sucralose manufacturing process
As mentioned earlier in the brief, sucralose is prepared using table sugar i.e. sucrose as the starting material. Selective chlorination is the process by which this table sugar alternative is prepared, and there are multiple routes through which this objective can be achieved. The most popular approach in sucralose production involves selective chlorination of sucrose-6-acetate. This step is then followed by the deprotection of the acetyl protecting group. The sucrose-6-acetate group is produced by selective acetylation of sucrose. This approach is more beneficial as compared to the other patented routes that can be used for sucralose production. Hence, it is popular as well.
Sucralose benefits
Some of the most useful traits of sucralose include:
1- 600 times sweeter than sugar but is closest to it in terms of taste as well.
2- No bitter aftertaste
3- Non-nutritive i.e. no calories.
4- Better shelf life as compared to some of the other alternatives.
5- Can withstand high temperature and acidic environment.
6- Can benefit the immune system
Sucralose side effects
Although sucralose has a safe profile overall, there are still a few concerns that cannot be ignored. It is reported to raise the blood pressure in some people, as well as negatively influence the insulin level. The chlorine atoms found in the sucralose structure can be detrimental to the useful bacteria found in the gut as well. However, this can be avoided by not using sucralose in high-temperature baking and cooking.
Sucralose Market size and Trend
Leading industrial experts believe that the 2020-2027 era will observe an exponential increase in sucralose business. This prediction is based on the assumption that the demand for artificial sweeteners is likely to increase with time. During this aforementioned period of seven years, the global sucralose market is expected to grow at a rate of 5.50%.
Sucralose bulk price
The exact price of sucralose API can vary from country to country, depending upon various export and import factors. However, the average price mark hovers around USD 30/Kg.
Sucralose manufacturers in China
Anhui Jinhe Industrial Co., Ltd
This is an industrial enterprise that is dedicated to the production of safe and healthy sweeteners. It specializes in the production of acesulfame, spice maltol, sucralose, and many other sweeteners. The industrial enterprise has been in the business since 2006.
Nantong Changhai Food Additive Co., Ltd (NiuTang)
Niutang is another name by which this leading life science manufacturing giant is known in China and the rest of the world. This manufacturing enterprise specializes in the production of quality food additives like sweeteners (sucralose in particular) and vitamins.
PharmaSources.com
Are you looking for more manufacturers of sucralose API? At pharmasources, you can search for hundreds of suppliers, API manufacturing companies and manufacturers of sucralose API in China, all of which are producing premium quality sucralose. Learn more about their modus operandi at pharmasources.
FAQ
What is sucralose made of?
It is made from table sugar in a multistep process, the most commonly used sucralose-based product is Splenda.
Is sucralose keto-friendly?
One has to be careful with sucralose, a little overdose and it can still kick you out of ketosis.
Is sucralose an artificial sweetener?
While it is made from real sugar, sucralose is still an artificial sweetener.
Does sucralose spike insulin?
Because it has the effect of triggering oral receptors, sucralose can increase insulin levels.
References
https://pubchem.ncbi.nlm.nih.gov/compound/Sucralose#section=Vapor-Pressure
https://healthyeating.sfgate.com/stevia-vs-sucralose-10342.html
https://wap.china.cn/Organic-Intermediate/166939367.html?t=description
https://www.sciencesnail.com/science/the-synthesis-of-sucralose-from-sucrose
https://www.databridgemarketresearch.com/reports/global-sucralose-market#:~:text=Global%20sucralose%20market%20is%20expected,forecast%20period%20of%202020%2D2027.
https://www.pharmacompass.com/price/sucralose
(All Rights Reserved)