Gut microbiota plays an important role in regulating immunity against infections. People who suffer from imbalance in gut microbiota (dysbiosis) are more susceptible to viral infection and other complications. An earlier study by the Faculty of Medicine of The Chinese University of Hong Kong, S.A.R., China (CU Medicine) has highlighted that severe gut dysbiosis exists in x patients.
A recent CU Medicine study reveals that 40% of Hong Kong, S.A.R., China people appeared to have significant gut dysbiosis comparable to that of COVID-19 patients, suggesting they have potentially impaired immunity. The Faculty has developed a microbiome immunity formula that targets gut dysbiosis. Clinical evidence showed COVID-19 patients who received the formula recovered better than those had only standard care. Data also suggests the formula can restore the balance of gut microbiota and boosts immunity.
A recent study by CU Medicine revealed a worrying fact that 40% of Hong Kong, S.A.R., China people appeared to have significant gut dysbiosis comparable to that of COVID-19 patients, suggesting they have potentially impaired immunity. CU Medicine has developed a microbiome immunity formula that targets gut dysbiosis. Compared with patients who had standard care, our research team found that more COVID-19 patients who received the microbiome immunity formula achieved complete symptom resolution, showed significantly reduced proinflammatory markers in their blood, had increased favourable bacteria in their stool; and developed neutralising antibody. Data also suggested that the formula can restore the balance of gut microbiota and boosts immunity.
40% of people in HK have moderate to severe gut dysbiosis related to impaired immunity
To evaluate the extent of dysbiosis in the general population, CU Medicine studied 1,000 subjects in Hong Kong, S.A.R., China aged between 18 and 83, and found that almost 40% of them had significant dysbiosis (i.e., impaired immunity) comparable to that of COVID-19 patients.
Professor Francis KL CHAN, Dean of Medicine and Director of the Centre for Gut Microbiota Research at CUHK remarked, "Gut dysbiosis is an important marker of impaired immunity. Our study findings showed 40% of Hong Kong, S.A.R., China people had evidence of significant dysbiosis comparable to that of COVID-19 patients which is alarming to us. We should take immediate action to restore the balance in gut microbiota and hence to help the public boost immunity against the threats of emerging infections such as COVID-19."
CUHK's microbiome immunity formula enhances recovery of COVID-19 patients
Using big data analysis and metagenomics derived from COVID-19 patients, researchers in CU Medicine has developed a unique oral microbiome formula that targets gut dysbiosis. Clinical data showed the recovery of COVID-19 patients who received the microbiome immunity formula outperformed those with standard care in many aspects. These include the achievement of complete symptom resolution; significant reduction of proinflammatory markers in their blood, increase in favourable bacteria in their stool and development of neutralising antibody.
Amid the third wave of COVID-19 outbreak in Hong Kong, S.A.R., China, the CU Medicine team recruited 55 hospitalised patients with COVID-19; 25 patients were treated with the microbiome immunity formula and 30 received standard care. Key findings are as follow:
100% of patients treated with the microbiome immunity formula achieved complete resolution of symptoms compared with half in the control group by week 2.
88% of patients in the microbiome immunity formula group developed neutralizing antibody compared with 63% in the control group.
The blood level of pro-inflammatory cytokines was significantly reduced in the microbiome immunity formula group, indicating that inflammation was under control.
The levels of favourable bacteria recovered from stool in patients receiving the microbiome immunity formula was significa...
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