Biosimilars that have entered Phase III clinical trials are listed below:
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Target | Representative original drug | Enterprise | Biosimilar name | Indication | R&D progress | |
CD20 | Rituximab (trade name: Rituxan) | Henlius | HLX01 | Rheumatoid arthritis | Phase Ⅲ clinical trial (recruiting) | |
Innovent | IBI301 | Diffuse large B-cell lymphoma | Phase Ⅲ clinical trial (recruiting) | |||
Hisun Pharmaceuticals | Recombinant Human/Mouse Chimeric Anti-CD20 Monoclonal Antibody Injection | Previously untreated CD20-positive diffuse large B-cell lymphoma | Phase Ⅲ clinical trial (recruiting) | |||
Sinocelltech | SCT400 Injection | CD20-positive diffuse large B-cell lymphoma (DLBCL) | Phase Ⅲ clinical trial (recruiting) | |||
EGFR | Cetuximab (trade name: Erbitux), nimotuzumab (trade name: Taixinsheng) | Biotech Pharma | Nimotuzumab Injection | Stage IVB, recurrent, or persistent squamous carcinoma of the cervix / metastatic esophageal squamous carcinoma / locally advanced or metastatic pancreatic cancer | Phase Ⅲ clinical trial (recruiting) | |
Kelun | Recombinant Anti-Epidermal Growth Factor Receptor (EGFR) Human-Mouse Chimeric Monoclonal Antibody Injection | First-line therapy of metastatic colorectal cancer | Phase Ⅲ clinical trial (having not recruited) | |||
MabTech | Recombinant Anti-EGFR Human-Mouse Chimeric Monoclonal Antibody Injection | Previously untreated wild-type RAS/BRAF metastatic colorectal cancer | Phase Ⅲ clinical trial (recruiting) | |||
VEGF | Bevacizumab (trade name: Avastin), ranibizumab (trade name: Lucentis) | Henlius | HLX04 | Metastatic colorectal cancer | Phase Ⅲ clinical trial (recruiting) | |
Chiatai Tianqing | TQ-B2302 | Non-squamous non-small cell lung cancer | Phase Ⅲ clinical trial (having not recruited) | |||
Innovent | IBI305 | Read More
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