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Xeno Series Serum-free Media for MDCK Cells

Category:

Bio Products

CAS NO:

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Shanghai BioEngine Sci-Tech Co., Ltd.

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Basic Info

CAS Number

Pharmacopoeia

In-house Standards

Grade

pharmaceutical grade

Is Manufacturer

YES

Product Description

Suitable for high-density cultures of MDCK cells, under serum-free and protein-free conditions. Supports rapid cell proliferation. Also suitable for MDCK adherent cells’ rapid suspension adaptation, supporting their efficient production of the influenza virus. Xeno series media has been applied in the first serum-free suspension cell-based production of the human influenza vaccine, which has obtained IND approval and is currently in clinical trials stage.

AI Product Description

*The following content is generated by AI and is for reference only.

The Xeno Series Serum-free Media for MDCK Cells is a specialized, chemically defined culture medium designed specifically for the cultivation of Madin-Darby Canine Kidney (MDCK) cells. As an advanced alternative to traditional serum-supplemented media, this formulation eliminates animal-derived components, thereby reducing the risk of viral contamination and ensuring greater batch-to-batch consistency. Consequently, it is ideal for applications requiring high reproducibility, such as vaccine production, toxicology testing, and the study of epithelial cell physiology. Unlike complex media containing undefined factors, the Xeno Series utilizes a precise blend of essential amino acids, vitamins, lipids, and trace elements tailored to support robust MDCK cell growth and morphology. The absence of bovine or other animal sera prevents the introduction of unknown variables that could interfere with downstream analytical processes or product purification. This makes the medium particularly valuable in biopharmaceutical manufacturing where regulatory compliance regarding xenogeneic materials is critical. While specific molecular formulas and CAS numbers are not applicable to this product in the conventional sense—as it is a proprietary mixture of numerous chemical compounds rather than a single pure substance—the individual ingredients within the base formulation adhere to strict quality standards. Each component is selected to mimic the natural physiological environment of canine kidney tissue, promoting optimal cell attachment, proliferation, and differentiation. Users can expect improved cell viability and higher yields compared to historical methods involving fetal bovine serum. The primary utility of this serum-free medium extends beyond basic research into industrial-scale applications. It supports the generation of high-quality viral vectors for gene therapy and facilitates the study of tight junction formation and polarized transport in epithelial monolayers. By providing a controlled and defined environment, researchers can better isolate experimental variables and achieve more reliable data. Furthermore, the transition to xeno-free conditions aligns with modern ethical guidelines and global trends toward animal-component-free bioprocessing. Overall, the Xeno Series Serum-free Media for MDCK Cells represents a significant advancement in cell culture technology, offering a safe, efficient, and compliant solution for both academic laboratories and commercial biomanufacturing facilities seeking superior performance and safety profiles.