*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Valsartan is a non-peptide angiotensin II receptor blocker (ARB) used primarily in hypertension management. Synthesized via <strong>catalytic coupling</strong>, its molecular formula is C<sub>24</sub>H<sub>29</sub>N<sub>5</sub>O<sub>3</sub> and CAS number is 137862-53-4.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Active pharmaceutical ingredient (API) for antihypertensive tablets and fixed-dose combinations.</li>
<li><strong>Cardiovascular Therapy:</strong> Treatment of heart failure and post-myocardial infarction to reduce mortality risks.</li>
<li><strong>Renal Protection:</strong> Management of diabetic nephropathy to slow kidney function decline.</li>
</ul>
<h3>Precautions</h3>
<p>Avoid use during pregnancy due to fetal toxicity. Store API in cool, dry conditions below 25°C with strict humidity control to prevent degradation. Ensure personnel wear appropriate PPE during handling to minimize inhalation or skin contact risks.</p>