*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Valsartan is a potent, selective <strong>Angiotensin II receptor blocker (ARB)</strong> used primarily in hypertension management. Synthesized via peptide coupling or condensation reactions, its molecular formula is <strong>C<sub>24</sub>H<sub>29</sub>N<sub>5</sub>O<sub>3</sub></strong> with CAS number <strong>137862-53-2</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical Manufacturing:</strong> Active Pharmaceutical Ingredient (API) for treating essential hypertension and heart failure.</li>
<li><strong>Cardiovascular Therapy:</strong> Reduces cardiovascular mortality risk post-myocardial infarction.</li>
<li><strong>Dosage Forms:</strong> Used in immediate-release tablets and combination therapies with hydrochlorothiazide.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in pregnancy due to fetal toxicity risks. Requires storage in tightly closed containers at controlled room temperature (20°C–25°C). Personnel must utilize appropriate PPE to avoid inhalation of fine dust during handling.</p>