Category:
Reagents for Biopharmaceuticals
CAS NO:
1143-70-0
Standard:
ChP,USP,BP,EP,
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Basic Info
CAS Number
1143-70-0
Pharmacopoeia
ChP,USP,BP,EP
Grade
Pharmaceutical Grade
Is Manufacturer
YES
Packaging & Delivery
Packaging Specification
25KG/Drum
Product Description
Common Name：Urolithin A
CAS Number：1143-70-0
Molecular Weight： 228.20000
Molecular Formula：C13H8O4
Specification: 98%
Urolithin A is an intestinal metabolite of ellagic acid with antioxidant and antiproliferative effects; inhibits T24 and Caco-2 cell growth with IC50 values of 43.9 and 49 μM, respectively
AI Product Description
*The following content is generated by AI and is for reference only.
Urolithin A is a naturally occurring postbiotic metabolite derived from the dietary intake of ellagitannins found in various fruits, including pomegranates, strawberries, and raspberries. Unlike its precursors, Urolithin A is not directly consumed but is produced by the human gut microbiota during digestion. This unique metabolic pathway has garnered significant scientific attention due to its potent biological activities, particularly concerning mitochondrial health and cellular longevity.
The molecular formula of Urolithin A is C13H8O6, with a corresponding CAS number of 4250-49-7. Structurally, it belongs to the class of dibenzopyrone derivatives, characterized by a rigid aromatic core that facilitates specific interactions with cellular targets. Its primary mechanism of action revolves around the induction of mitophagy, a critical quality control process where cells selectively degrade damaged mitochondria. By enhancing this recycling process, Urolithin A helps maintain mitochondrial efficiency, reduces oxidative stress, and improves overall cellular energy production.
In the realm of health and wellness, Urolithin A has emerged as a promising candidate for combating age-related decline. Clinical studies suggest its potential to improve muscle endurance, strength, and recovery in both older adults and athletes. Furthermore, research indicates anti-inflammatory properties that may benefit metabolic health and neuroprotection. These attributes have led to its rapid adoption in the nutraceutical industry, where it is formulated into high-quality supplements designed to support vitality and healthy aging.
While natural sources contain only trace amounts of Urolithin A, which varies significantly between individuals based on their gut flora composition, synthetic or biotechnologically produced versions ensure consistent dosing. As a result, Urolithin A represents a breakthrough in precision nutrition, offering a scientifically validated approach to sustaining physical performance and extending healthspan. With ongoing research expanding its therapeutic applications, it stands as a cornerstone compound in the future of preventative medicine and longevity science.
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