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CAS NO:
66-22-8
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ChP,
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Basic Info
CAS Number
66-22-8
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Uracil, chemically designated as 2,4-dioxopyrimidine, is a fundamental heterocyclic compound and one of the four primary nucleobases found in RNA. With the molecular formula C4H4N2O2 and a CAS registry number of 66-22-8, this white to off-white crystalline powder plays a critical role in biological systems. Unlike its DNA counterpart thymine, uracil pairs with adenine via two hydrogen bonds during the transcription and translation processes essential for protein synthesis. Structurally, it is a pyrimidine derivative that lacks the methyl group present in thymine, a distinction that facilitates its specific function within ribonucleic acid molecules.
In the pharmaceutical industry, uracil serves as a vital precursor for synthesizing various antiviral and anticancer drugs. It is frequently utilized in the production of 5-fluorouracil (5-FU), a potent chemotherapy agent widely used to treat cancers of the colon, breast, stomach, and pancreas. By interfering with DNA and RNA synthesis, these derivatives inhibit tumor growth. Beyond oncology, research into uracil derivatives continues to expand applications in treating metabolic disorders and developing novel diagnostic tools.
Furthermore, uracil is indispensable in biochemical research and molecular biology laboratories. It acts as a standard reagent for studying enzyme kinetics, particularly those involving RNA polymerases and nucleoside phosphorylases. Scientists also employ it in genetic engineering experiments to investigate mutation mechanisms and RNA stability. Its ability to participate in base-pairing makes it an excellent model for understanding nucleic acid structure and dynamics. In agriculture, certain uracil analogs are explored for their potential in regulating plant growth, although this area remains under active investigation. Overall, uracil stands as a cornerstone molecule bridging basic biochemistry and advanced medical therapeutics, underpinning countless advancements in life sciences and drug development globally.
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