*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Tofacitinib Impurity 2 is a critical synthetic intermediate and reference standard used in the quality control of the JAK inhibitor Tofacitinib. It is primarily generated during the <strong>pharmaceutical manufacturing</strong> process via specific coupling reactions. The compound features the molecular formula <strong>C15H18N6O4S</strong> and is identified by CAS number <strong>1470974-56-5</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Quality Control:</strong> Serves as an analytical standard for HPLC method validation.</li>
<li><strong>R&D:</strong> Utilized in stability testing to monitor degradation pathways.</li>
<li><strong>Regulatory Compliance:</strong> Supports impurity profiling for IND and NDA submissions.</li>
</ul>
<h3>Precautions</h3>
<p>Store at <strong>-20°C</strong> under inert atmosphere to prevent hydrolysis. Strict adherence to GMP guidelines is required when handling this substance for clinical batch release testing.</p>