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Other Specialized Reagents

Tipiracil

Category:

Other Specialized Reagents

CAS NO:

183204-72-0

Standard:

ChP,USP,BP,EP,JP,In-house Standards,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

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Seebio Biotech (Shanghai) Co., Ltd.

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Basic Info

CAS Number

183204-72-0

Pharmacopoeia

ChP,USP,BP,EP,JP,In-house Standards

Grade

Food Grade

Is Manufacturer

Packaging & Delivery

Packaging Specification

Minimum Order Quantity

1kg

Delivery Cycle

10-30days

Product Description

Tipiracil CAS Number 183204-72-0 Molecular Formula C9H12Cl2N4O2 Molecular Weight 183204-72-0 Package：1 Kg/Bag Function: thymidine phosphorylase inhibitor Application: For research use only Tags: Anti Tumor New Products.

Tipiralacil, also known as TPI, is a thymidine phosphorylase inhibitor (TPI). Tipiracil is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials.

TAS-102 is an antitumor agent composed of a combination of trifluorothymidine (FTD), a nucleoside that incorporates into DNA and inhibits a variety of genetic functions required for the proliferation of cancer cells, and tipiracil hydrochloride (TPI), an inhibitor of thymidine phosphorylase (which degrades FTD) that maintains an effective blood concentration of FTD. Tipiracil protects trifluridine from being broken down when taken orally.

Seebio also can supply Tipiracil intermediates as below:

PRODUCT NAME	CAS NO.	USAGE
5-Chloro-6-(chloromethyl)-2,4(1h,3h)-pyrimidinedione	73742-45-7	Tipiracil
3,4-dihydro-2H-pyrrol-5-amine hydrochloride (1:1)	7544-75-4	Tipiracil
6-(Chloromethyl)uracil	18592-13-7	Tipiracil

Thank you for your attention to Seebio Biotech (Shanghai) Co., Ltd.. If you’ve got any questions or comment, please

Name: Tipiracil HCl
CAS#: 183204-72-0
Chemical Formula: C9H12Cl2N4O2
Exact Mass: 278.03373
Molecular Weight: 279.12318
Elemental Analysis: C, 38.73; H, 4.33; Cl, 25.40; N, 20.07; O, 11.46
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO, not in water
Shelf Life: >2 years if stored properly