Product Description
AI Product Description
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>TIANDIDA® (Amifostine Injection) is a cytoprotective agent primarily used to mitigate renal toxicity and xerostomia associated with platinum-based chemotherapy. The active pharmaceutical ingredient, <strong>Amifostine</strong>, functions as an organic thiophosphate prodrug converted by alkaline phosphatase into its active thiol metabolite, WR-1065. Its molecular formula is <strong>C<sub>8</sub>H<sub>18</sub>N<sub>2</sub>O<sub>3</sub>PS</strong> with CAS Registry Number <strong>94357-96-1</strong>.</p>
<h3>Application</h3>
<ul>
<li><strong>Oncology:</strong> Standard prophylaxis for cumulative nephrotoxicity in patients receiving cisplatin for advanced ovarian cancer.</li>
<li><strong>Radiation Therapy:</strong> Reduction of severe dry mouth (xerostomia) in head and neck cancer patients undergoing radiotherapy.</li>
<li><strong>Chemoprotection:</strong> Adjunct therapy to reduce hematologic toxicity in high-dose chemotherapy regimens.</li>
</ul>
<h3>Precautions</h3>
<p>Strict clinical monitoring is required due to risks of hypotension and nausea/vomiting. Administration must occur under controlled medical settings with pre-hydration protocols. Store the injection at controlled room temperature between 20°C and 25°C, protecting from light and freezing conditions.</p>