*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Thiotepa</strong> is a potent alkylating agent used in oncology. Its core synthesis involves the oxidation of triethylenephosphoramide. Molecular formula: C<sub>6</sub>H<sub>12</sub>N<sub>3</sub>P; CAS No.: 52-24-4.</p>
<h3>Application</h3>
<ul>
<li>Oncology: Treatment of breast cancer and ovarian carcinoma.</li>
<li>Intravesical therapy: Management of non-muscle invasive bladder cancer.</li>
<li>Stem cell transplantation: Conditioning regimens prior to autologous transplant.</li>
</ul>
<h3>Precautions</h3>
<p>Strictly contraindicated for pregnant patients. Requires handling in negative pressure isolators due to carcinogenicity. Store under inert atmosphere at controlled temperatures below 25°C.</p>