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Preclinical Research Services
CAS NO:
2380-61-2
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ChP,
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Basic Info
CAS Number
2380-61-2
Pharmacopoeia
ChP
Grade
In-house Standards
Is Manufacturer
YES
Packaging & Delivery
Minimum Order Quantity
Any
Delivery Cycle
Negotiable
Product Description
Reference Standards &Impurity
AI Product Description
*The following content is generated by AI and is for reference only.
Thiamine, universally recognized as Vitamin B1, is a water-soluble vitamin essential for human health and metabolic function. Its molecular formula is C₁₂H₁₇ClN₄OS, reflecting its complex structure composed of a pyrimidine ring and a thiazole ring linked by a methylene bridge. The substance is identified by the CAS number 67-03-8 in scientific databases, ensuring precise identification across global regulatory frameworks. Naturally occurring in foods such as whole grains, legumes, pork, and yeast, Thiamine plays a critical role in carbohydrate metabolism. It acts as a vital coenzyme in the form of thiamine pyrophosphate (TPP), facilitating key enzymatic reactions including decarboxylation in the Krebs cycle and the synthesis of neurotransmitters like acetylcholine.
In the pharmaceutical industry, Thiamine is widely utilized to prevent and treat deficiency diseases, most notably beriberi, which manifests in wet or dry forms affecting the cardiovascular and nervous systems respectively. Wernicke-Korsakoff syndrome, often associated with chronic alcoholism, is another condition effectively managed through high-dose Thiamine supplementation. Beyond clinical applications, this compound is a staple ingredient in dietary supplements, multivitamin formulations, and fortified food products designed to combat nutritional gaps in modern diets. The industrial production of Thiamine involves chemical synthesis or fermentation processes, yielding highly pure crystalline powders suitable for various delivery methods including tablets, capsules, and injectable solutions.
Furthermore, Thiamine demonstrates significant utility in animal feed manufacturing, where it supports growth, energy metabolism, and overall vitality in livestock and poultry. Its stability varies depending on pH levels; it remains stable in acidic conditions but degrades rapidly in alkaline environments, necessitating careful formulation in commercial products. As a fundamental nutrient, adequate intake is crucial for maintaining neurological health, muscle function, and proper heart rhythm. With no known upper limit for toxicity due to its water-soluble nature, excess amounts are efficiently excreted through urine, making it a safe and reliable therapeutic agent. Global demand continues to rise driven by increasing awareness of nutritional health and the prevalence of metabolic disorders requiring targeted intervention.
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