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Active Pharmaceutical Ingredients

Tetracycline ointment

Category:

Active Pharmaceutical Ingredients

CAS NO:

60-54-8

Standard:

BP,

Price Range:

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Main Sales Markets:

North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

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Tianjin Sinomed Pharmaceutical Co., Ltd.

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Show Room

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Basic Info

CAS Number

60-54-8

Pharmacopoeia

Grade

Pharmaceutical Grade

Is Manufacturer

YES

Samples Provided

Packaging & Delivery

Packaging Specification

1 tube/box

Product Description

1.Product name:Tetracycline ointment

2.Specification: 1%,4g

3.Package:1 tube/box

4.Shelf life:36 months

5.Registration documents are available.

If you are interested in our products,please feel free to contact us.

AI Product Description

*The following content is generated by AI and is for reference only.

Tetracycline ointment is a widely utilized topical antibiotic formulation designed for the management of various superficial bacterial skin infections. The active pharmaceutical ingredient, tetracycline hydrochloride, belongs to the broad-spectrum tetracycline class of antibiotics. Its molecular formula is C22H24N2O8·HCl, and it carries the Chemical Abstracts Service (CAS) registry number 64-75-5. This compound functions by inhibiting bacterial protein synthesis; specifically, it binds reversibly to the 30S ribosomal subunit of susceptible bacteria, thereby preventing the attachment of aminoacyl-tRNA to the mRNA-ribosome complex. This mechanism effectively halts the growth and replication of Gram-positive and certain Gram-negative organisms, including *Staphylococcus aureus*, *Streptococcus pyogenes*, and *Haemophilus influenzae*. The primary clinical application of this ointment involves treating localized skin conditions such as impetigo, infected abrasions, minor burns, and folliculitis. It is frequently prescribed when oral administration is unnecessary or contraindicated, offering a direct delivery method that achieves high local concentrations at the site of infection while minimizing systemic exposure. The base of the ointment typically consists of petrolatum or similar emollients, which facilitate adherence to the skin and provide a protective barrier against external contaminants. Despite its efficacy, the use of tetracycline ointment requires careful consideration regarding potential adverse effects. Common side effects may include local irritation, redness, itching, or contact dermatitis. Furthermore, prolonged or inappropriate use can lead to the development of resistant bacterial strains or superinfections caused by non-susceptible organisms like fungi. Patients are advised to avoid applying the product near the eyes unless specifically directed by a healthcare professional, as ocular irritation is a known risk. Additionally, tetracyclines are generally contraindicated in pregnant women, nursing mothers, and children under eight years of age due to the risk of permanent tooth discoloration and inhibition of bone growth. As with all antibiotics, completing the full course of treatment as prescribed is essential to ensure complete eradication of the pathogen and prevent recurrence.