*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p>Tenofovir disoproxil Impurity 89 is a critical reference standard used in the quality control of antiviral drugs. This degradation product or synthetic intermediate possesses the molecular formula <strong>C<sub>19</sub>H<sub>26</sub>N<sub>5</sub>O<sub>4</sub>P</strong> and CAS number <strong>157098-69-2</strong>. It is typically generated during the phosphorylation stage of Tenofovir disoproxil fumarate manufacturing.</p>
<h3>Application</h3>
<ul>
<li><strong>Pharmaceutical QC:</strong> Used as an analytical standard for HPLC method validation to detect trace impurities in drug substances.</li>
<li><strong>R&D Studies:</strong> Employed in stability-indicating studies to monitor degradation pathways under stress conditions.</li>
<li><strong>Regulatory Compliance:</strong> Supports ICH Q3A guidelines by providing data for impurity profiling in new drug applications.</li>
</ul>
<h3>Precautions</h3>
<p>Store in a cool, dry place below -20°C under inert atmosphere. Handle with appropriate PPE including gloves and goggles to prevent dermal absorption. Not intended for human therapeutic use; strictly for laboratory analysis only.</p>