98.0% ~ 102.0% of Tenofovir Disoprovil Fumarate according to ENTERPRISE standards
*The following content is generated by AI and is for reference only.
<h3>Overview</h3>
<p><strong>Tenofovir Disoproxil Fumarate (TDF)</strong> is a prodrug of tenofovir, an acyclic nucleoside phosphonate analogue. Synthesized via esterification of tenofovir with isopropylidene and fumaric acid, its molecular formula is <strong>C₁₉H₂₈N₆O₁₀P</strong> with CAS No. <strong>147127-20-6</strong>.</p>
<h3>Application</h3>
<ul>
<li>HIV-1 treatment in combination antiretroviral therapy.</li>
<li>Chronic Hepatitis B virus (HBV) infection management.</li>
<li>Pre-exposure prophylaxis (PrEP) for high-risk populations.</li>
</ul>
<h3>Precautions</h3>
<p>Contraindicated in patients with severe renal impairment without dose adjustment. Store below 25°C in dry conditions. Monitor renal function and bone mineral density during long-term therapy.</p>